Reactome | CXXC1 and WDR82 bind SET1B complex

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CXXC1 and WDR82 bind SET1B complex Show undefined attributes

authored	[InstanceEdit:9823562] Orlic-Milacic, Marija, 2023-01-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9821473] Orlic-Milacic, Marija, 2022-12-05
dbId	9821476
displayName	CXXC1 and WDR82 bind SET1B complex
edited	[InstanceEdit:9828330] Orlic-Milacic, Marija, 2023-02-13
eventOf	[Pathway:R-HSA-9772755] Formation of WDR5-containing histone-modifying complexes - Homo sapiens
followingEvent	[Reaction:R-HSA-9821941] BOD1 binds SET1B complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-535610] CXXC1 [nucleoplasm] [Complex:R-HSA-9676269] SET1B complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9821474] WDR82 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9772918] Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex [LiteratureReference:9821494] Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes [LiteratureReference:9821501] Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS [LiteratureReference:9772762] Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	CXXC1 and WDR82 bind SET1B complex
orthologousEvent	[Reaction:R-CEL-9821476] CXXC1 and WDR82 bind SET1B complex - Caenorhabditis elegans [Reaction:R-DME-9821476] CXXC1 and WDR82 bind SET1B complex - Drosophila melanogaster [Reaction:R-SSC-9821476] CXXC1 and WDR82 bind SET1B complex - Sus scrofa [Reaction:R-BTA-9821476] CXXC1 and WDR82 bind SET1B complex - Bos taurus [Reaction:R-CFA-9821476] CXXC1 and WDR82 bind SET1B complex - Canis familiaris [Reaction:R-RNO-9821476] CXXC1 and WDR82 bind SET1B complex - Rattus norvegicus [Reaction:R-MMU-9821476] CXXC1 and WDR82 bind SET1B complex - Mus musculus
output	[Complex:R-HSA-9821472] SET1B complex:WDR82:CXXC1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9676264] Formation of the SET1B complex - Homo sapiens [BlackBoxEvent:R-HSA-1791158] Expression of CXXC1 - Homo sapiens
releaseDate	2023-03-29
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9827909] Van, Hieu, 2023-02-08 [InstanceEdit:9827910] Ge, Kai, 2023-02-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9821476
summation	[Summation:9821470] SET1B complex associates with CXXC1 (also known as CFP1) and...

Referrals

(hasEvent)	[Pathway:R-HSA-9772755] Formation of WDR5-containing histone-modifying complexes
(precedingEvent)	[Reaction:R-HSA-9821941] BOD1 binds SET1B complex