Reactome | Expression of DUXB in the embryo

Schema > BlackBoxEvent > Entries

Expression of DUXB in the embryo Show undefined attributes

authored	[InstanceEdit:9817766] May, Bruce, 2022-09-26
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9817937] May, Bruce, 2022-10-02
dbId	9817941
displayName	Expression of DUXB in the embryo
edited	[InstanceEdit:9817766] May, Bruce, 2022-09-26
eventOf	[Pathway:R-HSA-9819196] Zygotic genome activation (ZGA) - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9817251] DUXB gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9816444] Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons [LiteratureReference:9820768] Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development [LiteratureReference:9818480] Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation
maxDepth	1
modified	[InstanceEdit:9841067] May, Bruce, 2023-08-08
name	Expression of DUXB in the embryo
output	[EntityWithAccessionedSequence:R-HSA-9817297] DUXB [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9817258] DUX4, TPRXL, TPRX1, and TPRX2 bind the DUXB gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9817938] Positive gene expression regulation by 'DUX4:TPRXL:TPRX1:TPRX2:DUXB gene [nucleoplasm]'
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9817941
summation	[Summation:9820776] The DUXB gene is transcribed to yield mRNA which is translat...

Referrals

(hasEvent)

[Pathway:R-HSA-9819196] Zygotic genome activation (ZGA)

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