Reactome | AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine

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AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine Show undefined attributes

authored	[InstanceEdit:9817507] May, Bruce, 2022-09-21
catalystActivity	[CatalystActivity:480290] cytidine deaminase activity of AICDA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9817511] May, Bruce, 2022-09-23
dbId	9817513
displayName	AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine
edited	[InstanceEdit:9817507] May, Bruce, 2022-09-21
eventOf	[Pathway:R-HSA-9821002] Chromatin modifications during the maternal to zygotic transition (MZT) - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9817512] UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9817520] Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine - Mus musculus
input	[Complex:R-HSA-9822634] Chromatin with H3.3, H2AX, and 5mC [nucleoplasm] [SimpleEntity:R-ALL-9668967] H+ [nucleoplasm] [SimpleEntity:R-ALL-113518] H2O [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9841067] May, Bruce, 2023-08-08
name	AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine
output	[Complex:R-HSA-9817527] Chromatin with H3.3, H2AX, 5mC, U [nucleoplasm] [SimpleEntity:R-ALL-9822968] NH4+ [nucleoplasm]
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9817513
summation	[Summation:9819215] The first phase of active DNA demethylation in the male pron...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-9817512] UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3
(hasEvent)	[Pathway:R-HSA-9821002] Chromatin modifications during the maternal to zygotic transition (MZT)
(inferredTo)	[Reaction:R-MMU-9817520] Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine

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