Reactome | Maternal to zygotic transition (MZT)

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Maternal to zygotic transition (MZT) Show undefined attributes

authored	[InstanceEdit:9816375] May, Bruce, 2022-09-07
created	[InstanceEdit:9816422] May, Bruce, 2022-09-12
dbId	9816359
displayName	Maternal to zygotic transition (MZT)
doi	10.3180/R-HSA-9816359.1
edited	[InstanceEdit:9816375] May, Bruce, 2022-09-07
eventOf	[TopLevelPathway:R-HSA-1266738] Developmental Biology - Homo sapiens
figure	[Figure:9841890] /figures/ehld/R-HSA-9816359.svg
goBiologicalProcess	[GO_BiologicalProcess:9773524] maternal-to-zygotic transition of gene expression
hasDiagram	true
hasEHLD	true
hasEvent	[Pathway:R-HSA-9820841] M-decay: degradation of maternal mRNAs by maternally stored factors - Homo sapiens [Pathway:R-HSA-9821993] Replacement of protamines by nucleosomes in the male pronucleus - Homo sapiens [Pathway:R-HSA-9821002] Chromatin modifications during the maternal to zygotic transition (MZT) - Homo sapiens [Pathway:R-HSA-9819196] Zygotic genome activation (ZGA) - Homo sapiens [Pathway:R-HSA-9820865] Z-decay: degradation of maternal mRNAs by zygotically expressed factors - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9820751] A story of birth and death: mRNA translation and clearance at the onset of maternal-to-zygotic transition in mammals? [LiteratureReference:9820729] Dynamics of the epigenetic landscape during the maternal-to-zygotic transition [LiteratureReference:9820815] The maternal-to-zygotic transition revisited [LiteratureReference:9821459] The DNA methylation landscape of human early embryos [LiteratureReference:9821461] Epigenetic dynamics during preimplantation development [LiteratureReference:9821458] Maternal histone variants and their chaperones promote paternal genome activation and boost somatic cell reprogramming [LiteratureReference:9821449] The initiation of mammalian embryonic transcription: to begin at the beginning [LiteratureReference:9821821] Conservation and innovation in the DUX4-family gene network [LiteratureReference:9820699] From mother to embryo: A molecular perspective on zygotic genome activation [LiteratureReference:9823269] Remodelling the paternal chromatin at fertilization in mammals [LiteratureReference:9823271] Five questions toward mRNA degradation in oocytes and preimplantation embryos: when, who, to whom, how, and why??
maxDepth	3
modified	[InstanceEdit:9842372] Wright, Adam, 2023-08-26
name	Maternal to zygotic transition (MZT)
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9816359
summation	[Summation:9820979] Fertilization of the oocyte triggers the maternal-to-zygotic...

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[TopLevelPathway:R-HSA-1266738] Developmental Biology

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