Reactome | NFE2L2 negatively regulates IL8 mRNA degradation

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9796052] Tiwari, Krishna, 2022-08-04
dbId	9796054
displayName	NFE2L2 negatively regulates IL8 mRNA degradation
edited	[InstanceEdit:9841060] Tiwari, Krishna, 2023-08-08
eventOf	[Pathway:R-HSA-9818026] NFE2L2 regulating inflammation associated genes - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9795745] IL8 mRNA [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9795366] Activation of the Nrf2/antioxidant response pathway increases IL-8 expression
maxDepth	1
modified	[InstanceEdit:9842189] Matthews, Lisa, 2023-08-21
name	NFE2L2 negatively regulates IL8 mRNA degradation
regulatedBy	[NegativeRegulation:9795959] Negative regulation by 'p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm]'
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9796054
summation	[Summation:9817835] The dominant mechanism of NFE2L2-mediated IL8 induction is ...

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