NFE2L2 negatively regulates IL8 mRNA degradation

Stable Identifier
R-HSA-9796054
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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NFE2L2 negatively regulates IL8 mRNA degradation
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The dominant mechanism of NFE2L2-mediated IL8 induction is through mRNA stabilization (Zhang et al, 2005)
Literature References
PubMed ID Title Journal Year
16220540 Activation of the Nrf2/antioxidant response pathway increases IL-8 expression

Zhang, X, Song, H, Chen, HZ, Rovin, BH, Chen, X

Eur J Immunol 2005
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This event is regulated
Negatively by
Regulator
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm] (Homo sapiens)
Active Unit
p-S,T-NFE2L2 [nucleoplasm]
Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
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