Reactome | CD55 (DAF) promotes C3bBb/C4bC2a dissociation

Schema > Reaction > Entries

CD55 (DAF) promotes C3bBb/C4bC2a dissociation Show undefined attributes

authored	[InstanceEdit:981647] Jupe, S, 2010-10-26
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:977612] Jupe, S, 2010-10-20
dbId	977619
displayName	CD55 (DAF) promotes C3bBb/C4bC2a dissociation
edited	[InstanceEdit:983442] Jupe, S, 2010-11-01
eventOf	[Pathway:R-HSA-977606] Regulation of Complement cascade - Homo sapiens
input	[DefinedSet:R-HSA-981657] CD55:C3 convertase complexes [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:981632] Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes [LiteratureReference:981662] Localization of classical and alternative pathway regulatory activity within the decay-accelerating factor
maxDepth	1
modified	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
name	CD55 (DAF) promotes C3bBb/C4bC2a dissociation
orthologousEvent	[Reaction:R-SSC-977619] CD55 (DAF) promotes C3bBb/C4bC2a dissociation - Sus scrofa [Reaction:R-BTA-977619] CD55 (DAF) promotes C3bBb/C4bC2a dissociation - Bos taurus [Reaction:R-CFA-977619] CD55 (DAF) promotes C3bBb/C4bC2a dissociation - Canis familiaris [Reaction:R-MMU-977619] CD55 (DAF) promotes C3bBb/C4bC2a dissociation - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-166780] C2a [extracellular region] [Complex:R-HSA-981684] CD55:C3b [plasma membrane] [Complex:R-HSA-981639] CD55:C4b [plasma membrane] [EntityWithAccessionedSequence:R-HSA-182453] CFB(260-764) [extracellular region]
precedingEvent	[Reaction:R-HSA-981535] CD55 (DAF) binds C3bBb, C4bC2a - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2109568] Bradley, DT, 2012-02-13 [InstanceEdit:2109566] Fraczek, LA, 2012-02-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-977619
summation	[Summation:981529] Decay accelerating factor (DAF, CD55) is a widely distribute...

Referrals

(hasEvent)

[Pathway:R-HSA-977606] Regulation of Complement cascade

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