Reactome | Complement factor I complex formation

Schema > Reaction > Entries

Complement factor I complex formation Show undefined attributes

authored	[InstanceEdit:981647] Jupe, S, 2010-10-26
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:976791] Jupe, S, 2010-10-13
dbId	976801
displayName	Complement factor I complex formation
edited	[InstanceEdit:983442] Jupe, S, 2010-11-01
eventOf	[Pathway:R-HSA-977606] Regulation of Complement cascade - Homo sapiens
followingEvent	[Reaction:R-HSA-977359] Complement factor I binds to membrane-associated Factor H:C3b - Homo sapiens [Reaction:R-HSA-976810] Complement factor I binds to extracellular Factor H:C3b - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-976782] CFI(19-335) [extracellular region] [EntityWithAccessionedSequence:R-HSA-976750] CFI(340-583) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:976767] Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution [LiteratureReference:977356] Human complement factor I: analysis of cDNA-derived primary structure and assignment of its gene to chromosome 4
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Complement factor I complex formation
orthologousEvent	[Reaction:R-GGA-976801] Complement factor I complex formation - Gallus gallus [Reaction:R-XTR-976801] Complement factor I complex formation - Xenopus tropicalis [Reaction:R-SSC-976801] Complement factor I complex formation - Sus scrofa [Reaction:R-BTA-976801] Complement factor I complex formation - Bos taurus [Reaction:R-CFA-976801] Complement factor I complex formation - Canis familiaris [Reaction:R-RNO-976801] Complement factor I complex formation - Rattus norvegicus [Reaction:R-MMU-976801] Complement factor I complex formation - Mus musculus
output	[Complex:R-HSA-976749] CFI [extracellular region]
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2109568] Bradley, DT, 2012-02-13 [InstanceEdit:2109566] Fraczek, LA, 2012-02-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-976801
summation	[Summation:976753] Complement factor I (CFI) is a complex of one heavy and one ...

Referrals

(hasEvent)	[Pathway:R-HSA-977606] Regulation of Complement cascade
(precedingEvent)	[Reaction:R-HSA-976810] Complement factor I binds to extracellular Factor H:C3b [Reaction:R-HSA-977359] Complement factor I binds to membrane-associated Factor H:C3b