Reactome | Addition of a bifurcating GlcNAc to the N-glycan by MGAT3

Schema > Reaction > Entries

Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:975892] beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity of MGAT3 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:975912] Jassal, B, 2010-10-08
dbId	975926
displayName	Addition of a bifurcating GlcNAc to the N-glycan by MGAT3
edited	[InstanceEdit:975912] Jassal, B, 2010-10-08
eventOf	[Pathway:R-HSA-975574] Reactions specific to the hybrid N-glycan synthesis pathway - Homo sapiens
input	[SimpleEntity:R-ALL-975910] NGP [Golgi lumen] [SimpleEntity:R-ALL-914003] UDP-GlcNAc [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:975901] The bisecting GlcNAc on N-glycans inhibits growth factor signaling and retards mammary tumor progression [LiteratureReference:975908] Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Addition of a bifurcating GlcNAc to the N-glycan by MGAT3
orthologousEvent	[Reaction:R-BTA-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Bos taurus [Reaction:R-DDI-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Dictyostelium discoideum [Reaction:R-DME-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Drosophila melanogaster [Reaction:R-GGA-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Gallus gallus [Reaction:R-XTR-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Xenopus tropicalis [Reaction:R-DRE-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Danio rerio [Reaction:R-SSC-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Sus scrofa [Reaction:R-RNO-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Rattus norvegicus [Reaction:R-MMU-975926] Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 - Mus musculus
output	[OtherEntity:R-ALL-981613] Glycoprotein with bifurcating GlcNAc in position 3 [Golgi lumen]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-975926
summation	[Summation:975906] The addition of a bisecting GlcNAc to a complex N-glycan by ...

Referrals

(hasEvent)

[Pathway:R-HSA-975574] Reactions specific to the hybrid N-glycan synthesis pathway