Reactome | p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane]

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p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975133
displayName	p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane]
hasComponent	4 × [EntityWithAccessionedSequence:R-HSA-975187] p-IRAK2 [endosome membrane] [Complex:R-HSA-975159] p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
inDisease	false
literatureReference	[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
maxDepth	8
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9
producedByEvent	[Reaction:R-HSA-975160] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975133
updateTrackers	[UpdateTracker:9902893] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9871056] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9901524] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9953766] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9870331] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v38:[updateContainedComponent] [UpdateTracker:9869942] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9872914] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9901259] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9903452] Update Tracker - [Complex:975133] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR 7/8 or9 [endosome membrane] - v80:[updateContainedComponent]

Referrals

(updatedInstance)

(output)

[Reaction:R-HSA-975160] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9

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