Reactome | IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]

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IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] Show undefined attributes

catalystActivities	[CatalystActivity:975140] protein serine/threonine kinase activity of IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-HSA-975180] First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 - Homo sapiens
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975132
displayName	IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
hasComponent	4 × [EntityWithAccessionedSequence:R-HSA-975127] IRAK1 [endosome membrane] [Complex:R-HSA-975159] p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
inDisease	false
literatureReference	[LiteratureReference:975472] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction
maxDepth	8
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975132
updateTrackers	[UpdateTracker:9953942] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9873355] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9871230] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9903531] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901485] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9869970] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9870532] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9901215] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9902901] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9953942] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9873355] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9871230] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9903531] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901485] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9869970] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9870532] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9901215] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9902901] Update Tracker - [Complex:975132] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent]
(input)	[Reaction:R-HSA-975180] First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9
(physicalEntity)	[CatalystActivity:975140] protein serine/threonine kinase activity of IRAK1:p-S,2T-IRAK4 :oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]

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