Reactome | ORC6 is phosphorylated on T195

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ORC6 is phosphorylated on T195 Show undefined attributes

authored	[InstanceEdit:9734666] Kusic-Tisma, Jelena, 2021-06-18
category	uncertain
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9734683] Orlic-Milacic, Marija, 2021-06-18
dbId	9734687
displayName	ORC6 is phosphorylated on T195
edited	[InstanceEdit:9750784] Orlic-Milacic, Marija, 2021-08-16
eventOf	[Pathway:R-HSA-68616] Assembly of the ORC complex at the origin of replication - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9734713] ORC6 translocates to the nucleus - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-9734662] ORC6:KPNA1,KPNA6:KPNB1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9734659] Assembly of the human origin recognition complex occurs through independent nuclear localization of its components
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	ORC6 is phosphorylated on T195
orthologousEvent	[BlackBoxEvent:R-SPO-9734687] ORC6 is phosphorylated on T195 - Schizosaccharomyces pombe [BlackBoxEvent:R-DME-9734687] ORC6 is phosphorylated on T195 - Drosophila melanogaster [BlackBoxEvent:R-GGA-9734687] ORC6 is phosphorylated on T195 - Gallus gallus [BlackBoxEvent:R-XTR-9734687] ORC6 is phosphorylated on T195 - Xenopus tropicalis [BlackBoxEvent:R-DRE-9734687] ORC6 is phosphorylated on T195 - Danio rerio [BlackBoxEvent:R-SSC-9734687] ORC6 is phosphorylated on T195 - Sus scrofa [BlackBoxEvent:R-BTA-9734687] ORC6 is phosphorylated on T195 - Bos taurus [BlackBoxEvent:R-RNO-9734687] ORC6 is phosphorylated on T195 - Rattus norvegicus [BlackBoxEvent:R-MMU-9734687] ORC6 is phosphorylated on T195 - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-9734684] p-T195-ORC6:KPNA1,KPNA6:KPNB1 [cytosol]
precedingEvent	[Reaction:R-HSA-9734670] ORC6 binds KPNA1 or KPNA6 - Homo sapiens
releaseDate	2021-09-15
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9734687
summation	[Summation:9734685] ORC6 is phosphorylated on threonine residue 195 (T195), a CD...

Referrals

(hasEvent)	[Pathway:R-HSA-68616] Assembly of the ORC complex at the origin of replication
(precedingEvent)	[BlackBoxEvent:R-HSA-9734713] ORC6 translocates to the nucleus