Reactome | Alkylating DNA damage induced by chemotherapeutic drugs

Schema > Pathway > Entries

authored	[InstanceEdit:9730922] Orlic-Milacic, Marija, 2021-05-11
created	[InstanceEdit:9730735] Orlic-Milacic, Marija, 2021-05-10
dbId	9730737
displayName	Alkylating DNA damage induced by chemotherapeutic drugs
doi	10.3180/R-HSA-9730737.1
edited	[InstanceEdit:9749854] Orlic-Milacic, Marija, 2021-08-06
eventOf	[Pathway:R-HSA-73929] Base-Excision Repair, AP Site Formation - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-9730736] Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA - Homo sapiens [BlackBoxEvent:R-HSA-9730767] Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9616000] Balancing repair and tolerance of DNA damage caused by alkylating agents
maxDepth	2
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Alkylating DNA damage induced by chemotherapeutic drugs
releaseDate	2021-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9749858] Kadambat Nair, Sisira, 2021-07-28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9730737
summation	[Summation:9750131] This pathway describes how chemotherapeutic drugs commonly u...

(hasEvent)

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