Alkylating DNA damage induced by chemotherapeutic drugs

Stable Identifier
R-HSA-9730737
Type
Pathway
Species
Homo sapiens
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This pathway describes how chemotherapeutic drugs commonly used in cancer treatment produce alkylating DNA damage that is repaired through the base excision repair (BER) pathway. For review, please refer to Fu et al. 2012.

Literature References
PubMed ID Title Journal Year
22237395 Balancing repair and tolerance of DNA damage caused by alkylating agents

Fu, D, Calvo, JA, Samson, LD

Nat. Rev. Cancer 2012
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