Reactome | STAT3-activating ALK mutants:STAT3 [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9711943] protein tyrosine kinase activity of STAT3-activating ALK mutants:STAT3 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9712085] ALK mutants phosphorylate STAT3 - Homo sapiens
created	[InstanceEdit:9711934] Rothfels, Karen, 2021-01-13
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9711935
disease	[Disease:1500689] cancer
displayName	STAT3-activating ALK mutants:STAT3 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-539044] STAT3 [cytosol] [CandidateSet:R-HSA-9711944] STAT3-activating ALK mutants [cytosol]
inDisease	true
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9724130] Rothfels, Karen, 2021-03-22
name	STAT3-activating ALK mutants:STAT3
producedByEvent	[Reaction:R-HSA-9712079] ALK mutants bind STAT3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9711935

(output)	[Reaction:R-HSA-9712079] ALK mutants bind STAT3
(input)	[Reaction:R-HSA-9712085] ALK mutants phosphorylate STAT3
(physicalEntity)	[CatalystActivity:9711943] protein tyrosine kinase activity of STAT3-activating ALK mutants:STAT3 [cytosol]

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