Reactome | GSDME(1-270) D14Y [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9710398] Shamovsky, Veronica, 2020-12-30
crossReference	[DatabaseIdentifier:12020961] Mondo:0004989
dbId	9710450
disease	[Disease:1500689] cancer [Disease:9701259] breast carcinoma
displayName	GSDME(1-270) D14Y [cytosol]
endCoordinate	270
hasModifiedResidue	[ReplacedResidue:9710401] L-aspartic acid 14 replaced with L-tyrosine
inDisease	true
literatureReference	[LiteratureReference:9710028] Gasdermin E suppresses tumour growth by activating anti-tumour immunity
maxDepth	1
memberOf	[CandidateSet:R-HSA-9710467] GSDME variant [cytosol] - Homo sapiens
name	GSDME(1-270) D14Y Gasdermin-E (1-270) D14Y Gasdermin-E, N-terminal
referenceEntity	[ReferenceGeneProduct:uniprot:O60443] UniProt:O60443 GSDME
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9710450
startCoordinate	1

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