Reactome | TBK1:pp1ab-nsp13 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9705081] Shamovsky, Veronica, 2020-10-21
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9705087
disease	[Disease:9683912] COVID-19
displayName	TBK1:pp1ab-nsp13 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-COV-9694642] pp1ab-nsp13 [cytosol] [EntityWithAccessionedSequence:R-HSA-166267] TBK1 [cytosol]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:9705013] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing [LiteratureReference:9705074] Evasion of Type I Interferon by SARS-CoV-2
maxDepth	2
modified	[InstanceEdit:9767585] Shamovsky, Veronica, 2022-02-28
name	TBK1:pp1ab-nsp13
negativelyRegulates	[NegativeRegulation:9705329] Negative regulation by 'TBK1:pp1ab-nsp13 [cytosol]'
producedByEvent	[Reaction:R-HSA-9705082] SARS-CoV-2 nsp13 binds TBK1 - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9705087

(regulator)	[NegativeRegulation:9705329] Negative regulation by 'TBK1:pp1ab-nsp13 [cytosol]'
(output)	[Reaction:R-HSA-9705082] SARS-CoV-2 nsp13 binds TBK1

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