Reactome | TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol]

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TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9702022] TFG(1-138)-p-7Y ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9702022] TFG(1-138)-p-7Y ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9702020] Rothfels, Karen, 2020-09-28
crossReference	[DatabaseIdentifier:12020842] Mondo:0020325 [DatabaseIdentifier:9700456] COSMIC:COSF424
dbId	9702019
disease	[Disease:9699595] anaplastic large cell lymphoma [Disease:1500689] cancer
displayName	TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol]
endCoordinate	138
hasModifiedResidue	[FragmentInsertionModification:9699849] Insertion of residues 1058 to 1620 at 139 from UniProt:Q9UM73 ALK [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
inDisease	true
literatureReference	[LiteratureReference:9699785] TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations
maxDepth	1
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	TFG(1-138)-p-7Y-ALK(1058-1620) fusion Protein TFG TFG_HUMAN TFGs-ALK
referenceEntity	[ReferenceGeneProduct:uniprot:Q92734] UniProt:Q92734 TFG
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9702019
startCoordinate	1
updateTrackers	[UpdateTracker:9905505] Update Tracker - [EntityWithAccessionedSequence:9702019] TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905505] Update Tracker - [EntityWithAccessionedSequence:9702019] TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
(hasComponent)	[Complex:R-HSA-9702022] TFG(1-138)-p-7Y ALK(1058-1620) fusion dimer [cytosol]

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