Reactome | p-7Y ALK G1201E [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9701866] p-7Y ALK G1201E dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9701866] p-7Y ALK G1201E dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9701862] Rothfels, Karen, 2020-09-28
crossReference	[DatabaseIdentifier:12021093] Mondo:0015075 [DatabaseIdentifier:9701792] COSMIC:COSV66557297
dbId	9701868
disease	[Disease:6802256] thyroid carcinoma
displayName	p-7Y ALK G1201E [plasma membrane]
endCoordinate	1620
hasModifiedResidue	[ReplacedResidue:9701815] glycine 1201 replaced with L-glutamic acid [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
inDisease	true
literatureReference	[LiteratureReference:9701769] Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene
maxDepth	1
name	p-7Y ALK G1201E ALK tyrosine kinase receptor ALK_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UM73] UniProt:Q9UM73 ALK
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9701868
startCoordinate	19

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