Reactome | ALK L1198P [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9701840] ALK L1198P dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9701840] ALK L1198P dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9701825] Rothfels, Karen, 2020-09-28
dbId	9701826
displayName	ALK L1198P [plasma membrane]
endCoordinate	1620
hasModifiedResidue	[ReplacedResidue:9701801] L-leucine 1198 replaced with L-proline
inDisease	false
literatureReference	[LiteratureReference:9701773] ALK mutations conferring differential resistance to structurally diverse ALK inhibitors
maxDepth	1
modified	[InstanceEdit:9715307] Rothfels, Karen, 2021-02-17
name	ALK L1198P ALK tyrosine kinase receptor ALK_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UM73] UniProt:Q9UM73 ALK
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9701826
startCoordinate	19

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