Reactome | SIN3A:ACK685-p-Y705,S727 STAT3 dimer:IL2RG gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9701470] Rothfels, Karen, 2020-09-26
dbId	9701471
displayName	SIN3A:ACK685-p-Y705,S727 STAT3 dimer:IL2RG gene [nucleoplasm]
hasComponent	[Complex:R-HSA-9701472] AcK685-p-Y705,S727 STAT3 dimer:SIN3A [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9701417] IL2RG gene [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:9701314] The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3
maxDepth	4
name	SIN3A:ACK685-p-Y705,S727 STAT3 dimer:IL2RG gene
negativelyRegulates	[NegativeGeneExpressionRegulation:9701545] Negative gene expression regulation by 'SIN3A:ACK685-p-Y705,S727 STAT3 dimer:IL2RG gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-9701557] AcK685-p-Y705,S727 STAT3 and SIN3A bind the IL2RG promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9701471

(output)	[Reaction:R-HSA-9701557] AcK685-p-Y705,S727 STAT3 and SIN3A bind the IL2RG promoter
(regulator)	[NegativeGeneExpressionRegulation:9701545] Negative gene expression regulation by 'SIN3A:ACK685-p-Y705,S727 STAT3 dimer:IL2RG gene [nucleoplasm]'

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