Reactome | p-7Y ALK G1128A [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9700563] p-7Y ALK G1128A dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9700563] p-7Y ALK G1128A dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9700471] Rothfels, Karen, 2020-09-16
crossReference	[DatabaseIdentifier:12021383] Mondo:0005072 [DatabaseIdentifier:9699912] COSMIC:COSV66582675
dbId	9700484
disease	[Disease:9671652] neuroblastoma [Disease:8853117] lung adenocarcinoma
displayName	p-7Y ALK G1128A [plasma membrane]
endCoordinate	1620
hasModifiedResidue	[ReplacedResidue:9699892] glycine 1128 replaced with L-alanine [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
inDisease	true
literatureReference	[LiteratureReference:9700415] Crystal structures of anaplastic lymphoma kinase in complex with ATP competitive inhibitors
maxDepth	1
name	p-7Y ALK G1128A ALK tyrosine kinase receptor ALK_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UM73] UniProt:Q9UM73 ALK
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9700484
startCoordinate	19

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