Reactome | STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol]

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STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9700524] STRN(1-137)-p-7Y ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9700524] STRN(1-137)-p-7Y ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9700471] Rothfels, Karen, 2020-09-16
crossReference	[DatabaseIdentifier:12020833] Mondo:0005061
dbId	9700467
disease	[Disease:8853117] lung adenocarcinoma [Disease:6802256] thyroid carcinoma
displayName	STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol]
endCoordinate	137
hasModifiedResidue	[FragmentInsertionModification:9700449] Insertion of residues 1058 to 1620 at 138 from UniProt:Q9UM73 ALK [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
inDisease	true
literatureReference	[LiteratureReference:9700342] Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing [LiteratureReference:9711822] Identification of a recurrent STRN/ALK fusion in thyroid carcinomas
maxDepth	1
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	STRN(1-137)-p-7Y-ALK(1058-1620) fusion Striatin
referenceEntity	[ReferenceGeneProduct:uniprot:O43815] UniProt:O43815 STRN
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9700467
startCoordinate	1
updateTrackers	[UpdateTracker:9905439] Update Tracker - [EntityWithAccessionedSequence:9700467] STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905439] Update Tracker - [EntityWithAccessionedSequence:9700467] STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
(hasComponent)	[Complex:R-HSA-9700524] STRN(1-137)-p-7Y ALK(1058-1620) fusion dimer [cytosol]

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