Reactome | EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9700018] EML4(1-223)-p-7Y ALK(1059-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9700018] EML4(1-223)-p-7Y ALK(1059-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9699845] Rothfels, Karen, 2020-09-14
crossReference	[DatabaseIdentifier:12020794] Mondo:0005233
dbId	9699903
disease	[Disease:1247848] non-small cell lung carcinoma
displayName	EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol]
endCoordinate	223
hasModifiedResidue	[FragmentInsertionModification:9699847] Insertion of residues 1059 to 1620 at 224 from UniProt:Q9UM73 ALK [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
inDisease	true
literatureReference	[LiteratureReference:9699710] Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
maxDepth	1
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	EML4(1-223)-p-7Y-ALK(1059-1620) fusion Echinoderm microtubule-associated protein-like 4 EMAL4_HUMAN variant 3a
referenceEntity	[ReferenceGeneProduct:uniprot:Q9HC35] UniProt:Q9HC35 EML4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9699903
startCoordinate	1
updateTrackers	[UpdateTracker:9905838] Update Tracker - [EntityWithAccessionedSequence:9699903] EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol] - v85:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905838] Update Tracker - [EntityWithAccessionedSequence:9699903] EML4(1-223)-p-7Y-ALK(1059-1620) fusion [cytosol] - v85:[modifyName]
(hasComponent)	[Complex:R-HSA-9700018] EML4(1-223)-p-7Y ALK(1059-1620) fusion dimer [cytosol]

Cite Us!