Reactome | FLT3 N676S [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9682396] kinase domain mutants of FLT3 [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9695764] FLT3 N676S dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9695764] FLT3 N676S dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9695711] Rothfels, Karen, 2020-07-15
crossReference	[DatabaseIdentifier:12020781] Mondo:0011962 [DatabaseIdentifier:9695687] COSMIC:COSV54069454
dbId	9695717
disease	[Disease:1500689] cancer [Disease:2317358] endometrial cancer
displayName	FLT3 N676S [plasma membrane]
endCoordinate	993
hasModifiedResidue	[ReplacedResidue:9695625] L-asparagine 676 replaced with L-serine
inDisease	true
maxDepth	1
name	FLT3 N676S STK-1
referenceEntity	[ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9695717
startCoordinate	27

(hasCandidate)	[CandidateSet:R-HSA-9682396] kinase domain mutants of FLT3 [plasma membrane]
(hasComponent)	[Complex:R-HSA-9695764] FLT3 N676S dimer [plasma membrane]

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