Reactome | Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching

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Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching Show undefined attributes

authored	[InstanceEdit:9686443] Orlic-Milacic, Marija, 2020-04-30
catalystActivity	[CatalystActivity:9685678] RNA-directed RNA polymerase activity of SARS-CoV-1 gRNA:RTC [double membrane vesicle viral factory outer membrane]
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:9684675] double membrane vesicle viral factory outer membrane
created	[InstanceEdit:9685641] Orlic-Milacic, Marija, 2020-04-24
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9685639
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching
edited	[InstanceEdit:9687600] Orlic-Milacic, Marija, 2020-05-11
eventOf	[Pathway:R-HSA-9682708] Transcription of SARS-CoV-1 sgRNAs - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9685681] Synthesis of SARS-CoV-1 plus strand subgenomic mRNAs - Homo sapiens
input	[SimpleEntity:R-ALL-6806881] NTP [cytosol] [Complex:R-COV-9681659] SARS-CoV-1 gRNA:RTC [double membrane vesicle viral factory outer membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9685731] Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus [LiteratureReference:9682792] Mechanisms and enzymes involved in SARS coronavirus genome expression [LiteratureReference:9685734] Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching
orthologousEvent	[BlackBoxEvent:R-HSA-9694344] Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching - Homo sapiens
output	[SimpleEntity:R-ALL-111294] PPi [cytosol] [Complex:R-COV-9713317] SARS-CoV-1 minus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane]
regulatedBy	[PositiveRegulation:9685695] Positive regulation by 'N [cytosol]'
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9685639
summation	[Summation:9685688] SARS-CoV-1 encodes eight subgenomic RNAs, mRNA2 to mRNA9. mR...
updateTrackers	[UpdateTracker:9776435] Update Tracker - [BlackBoxEvent:9685639] Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching - v76:[add_removeOutput] [UpdateTracker:9776112] Update Tracker - [BlackBoxEvent:9685639] Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching - v77:[add_removeRegulator]

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(updatedInstance)	[UpdateTracker:9776435] Update Tracker - [BlackBoxEvent:9685639] Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching - v76:[add_removeOutput] [UpdateTracker:9776112] Update Tracker - [BlackBoxEvent:9685639] Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching - v77:[add_removeRegulator]
(hasEvent)	[Pathway:R-HSA-9682708] Transcription of SARS-CoV-1 sgRNAs
(precedingEvent)	[BlackBoxEvent:R-HSA-9685681] Synthesis of SARS-CoV-1 plus strand subgenomic mRNAs

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