Reactome | nsp16 binds VHL

Schema > Reaction > Entries

authored	[InstanceEdit:9686443] Orlic-Milacic, Marija, 2020-04-30
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9683451] Orlic-Milacic, Marija, 2020-04-16
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9683455
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	nsp16 binds VHL
edited	[InstanceEdit:9687600] Orlic-Milacic, Marija, 2020-05-11
eventOf	[Pathway:R-HSA-9682706] Replication of the SARS-CoV-1 genome - Homo sapiens
input	[EntityWithAccessionedSequence:R-COV-9678289] pp1ab-nsp16 [cytosol] [EntityWithAccessionedSequence:R-HSA-391423] VHL [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9683452] VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	nsp16 binds VHL
orthologousEvent	[Reaction:R-HSA-9694520] nsp16 binds VHL - Homo sapiens
output	[Complex:R-HSA-9683453] nsp16:VHL [cytosol]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9683455
summation	[Summation:9683456] Human von Hippel Lindau (VHL) protein, a tumor suppressor th...

(hasEvent)

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