Reactome | nsp15 binds nsp8

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nsp15 binds nsp8 Show undefined attributes

authored	[InstanceEdit:9686443] Orlic-Milacic, Marija, 2020-04-30
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9683395] Orlic-Milacic, Marija, 2020-04-14
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9683393
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	nsp15 binds nsp8
edited	[InstanceEdit:9687600] Orlic-Milacic, Marija, 2020-05-11
eventOf	[Pathway:R-HSA-9683439] Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC) - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9705961] nsp15 cleaves viral poly(U)-RNA - Homo sapiens [BlackBoxEvent:R-HSA-9686005] nsp3 binds to nsp7-8 and nsp12-16 - Homo sapiens
input	[Complex:R-COV-9682715] nsp15 hexamer [cytosol] [Complex:R-COV-9682616] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9683401] The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	nsp15 binds nsp8
orthologousEvent	[Reaction:R-HSA-9694539] nsp15 binds nsp8 - Homo sapiens
output	[Complex:R-COV-9683403] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol]
precedingEvent	[Reaction:R-HSA-9682718] nsp15 forms a hexamer - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9683393
summation	[Summation:9683399] Nonstructural protein 15 (nsp15) of the SARS coronavirus (SA...
updateTrackers	[UpdateTracker:9775318] Update Tracker - [Reaction:9683393] nsp15 binds nsp8 - v79:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9775318] Update Tracker - [Reaction:9683393] nsp15 binds nsp8 - v79:[modifyText]
(precedingEvent)	[BlackBoxEvent:R-HSA-9705961] nsp15 cleaves viral poly(U)-RNA [BlackBoxEvent:R-HSA-9686005] nsp3 binds to nsp7-8 and nsp12-16
(hasEvent)	[Pathway:R-HSA-9683439] Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)

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