Reactome | p-7Y-KIT T417_D419delinsY [plasma membrane]

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p-7Y-KIT T417_D419delinsY [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9680163] p7Y-KIT T417-D419delinsY dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9680163] p7Y-KIT T417-D419delinsY dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9680162] Rothfels, Karen, 2020-03-25
crossReference	[DatabaseIdentifier:12021306] Mondo:0007950 [DatabaseIdentifier:9832107] COSMIC:COSV55422105 [DatabaseIdentifier:9832108] COSMIC:COSV55399723 [DatabaseIdentifier:9832106] COSMIC:COSV55395053 [DatabaseIdentifier:9832104] COSMIC:COSV106086453 [DatabaseIdentifier:9832109] COSMIC:COSM24877
dbId	9680165
disease	[Disease:1500689] cancer [Disease:9680112] mastocytosis
displayName	p-7Y-KIT T417_D419delinsY [plasma membrane]
endCoordinate	976
hasModifiedResidue	[FragmentReplacedModification:9680111] Replacement of residues 417 to 419 by Y [ModifiedResidue:205176] O4'-phospho-L-tyrosine at 568 [ModifiedResidue:205169] O4'-phospho-L-tyrosine at 570 [ModifiedResidue:205278] O4'-phospho-L-tyrosine at 703 [ModifiedResidue:205171] O4'-phospho-L-tyrosine at 721 [ModifiedResidue:205288] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:205235] O4'-phospho-L-tyrosine at 823 [ModifiedResidue:205246] O4'-phospho-L-tyrosine at 936
inDisease	true
literatureReference	[LiteratureReference:9679981] Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations
maxDepth	1
modified	[InstanceEdit:9832110] Orlic-Milacic, Marija, 2023-03-28
name	p-7Y-KIT T417_D419delinsY
referenceEntity	[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9680165
startCoordinate	26
updateTrackers	[UpdateTracker:9905689] Update Tracker - [EntityWithAccessionedSequence:9680165] p-7Y-KIT T417_D419delinsY [plasma membrane] - v85:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905689] Update Tracker - [EntityWithAccessionedSequence:9680165] p-7Y-KIT T417_D419delinsY [plasma membrane] - v85:[modifyName]
(hasComponent)	[Complex:R-HSA-9680163] p7Y-KIT T417-D419delinsY dimer [plasma membrane]

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