Reactome | PDGFR:type I PDGFR-binding TKIs [plasma membrane]

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PDGFR:type I PDGFR-binding TKIs [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9674083] Rothfels, Karen, 2020-01-10
dbId	9674082
displayName	PDGFR:type I PDGFR-binding TKIs [plasma membrane]
hasComponent	[Complex:R-HSA-389079] PDGF alpha receptor: PDGF dimers [plasma membrane] [DefinedSet:R-ALL-9674075] type I PDGFR-binding tyrosine kinase inhibitors [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Mus musculus [Complex:R-RNO-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Canis familiaris [Complex:R-BTA-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Bos taurus [Complex:R-SSC-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Sus scrofa [Complex:R-DRE-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Danio rerio [Complex:R-GGA-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Gallus gallus [Complex:R-DME-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	6
modified	[InstanceEdit:9674454] Rothfels, Karen, 2020-01-13
name	PDGFR:type I PDGFR-binding TKIs
negativelyRegulates	[NegativeRegulation:9674157] Negative regulation by 'PDGFR:type I PDGFR-binding TKIs [plasma membrane]'
producedByEvent	[Reaction:R-HSA-9674093] PDGFRs bind type I TKI - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9674082

Referrals

(output)	[Reaction:R-HSA-9674093] PDGFRs bind type I TKI
(regulator)	[NegativeRegulation:9674157] Negative regulation by 'PDGFR:type I PDGFR-binding TKIs [plasma membrane]'

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