Reactome | 12xCbxE-3D-F9(47-461) R226Q [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

12xCbxE-3D-F9(47-461) R226Q [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9673408] Shamovsky, Veronica, 2020-01-07
crossReference	[DatabaseIdentifier:9673401] ClinGen:CA121128
dbId	9673415
displayName	12xCbxE-3D-F9(47-461) R226Q [extracellular region]
endCoordinate	461
hasModifiedResidue	[ReplacedResidue:9673413] L-arginine 226 replaced with L-glutamine [ModifiedResidue:140824] L-gamma-carboxyglutamic acid at 86 [ModifiedResidue:140835] L-gamma-carboxyglutamic acid at 82 [ModifiedResidue:140836] L-gamma-carboxyglutamic acid at 79 [ModifiedResidue:140878] L-gamma-carboxyglutamic acid at 76 [ModifiedResidue:140879] L-gamma-carboxyglutamic acid at 73 [ModifiedResidue:140880] L-gamma-carboxyglutamic acid at 72 [ModifiedResidue:140881] L-gamma-carboxyglutamic acid at 67 [ModifiedResidue:140882] L-gamma-carboxyglutamic acid at 66 [ModifiedResidue:140883] L-gamma-carboxyglutamic acid at 63 [ModifiedResidue:140884] L-gamma-carboxyglutamic acid at 61 [ModifiedResidue:140885] L-gamma-carboxyglutamic acid at 54 [ModifiedResidue:8865023] L-gamma-carboxyglutamic acid at 53 [ModifiedResidue:140818] (2S,3R)-3-hydroxyaspartic acid at 110
inDisease	false
literatureReference	[LiteratureReference:140887] Nucleotide sequence of the gene for human factor IX (antihemophilic factor B) [LiteratureReference:140890] The occurrence of beta-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens [LiteratureReference:9673380] Functional consequences of an arginine180 to glutamine mutation in factor IX Hilo
maxDepth	1
memberOf	[CandidateSet:R-HSA-9673225] F9 zymogen variant [extracellular region] - Homo sapiens
name	12xCbxE-3D-F9(47-461) R226Q 12xCbxE-3D-F9 R226Q factor IX R226Q
referenceEntity	[ReferenceGeneProduct:uniprot:P00740] UniProt:P00740 F9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9673415
startCoordinate	47

Referrals

(hasMember)

[CandidateSet:R-HSA-9673225] F9 zymogen variant [extracellular region]

© 2026 Reactome

Cite Us!