Reactome | WNT5 binds FZD7

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WNT5 binds FZD7 Show undefined attributes

authored	[InstanceEdit:9664405] Murillo, Julieth, 2019-10-22 [InstanceEdit:9673371] Jassal, Bijay, 2020-01-07
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9673290] Murillo, Julieth, 2020-01-07
dbId	9673349
displayName	WNT5 binds FZD7
edited	[InstanceEdit:9673371] Jassal, Bijay, 2020-01-07 [InstanceEdit:9673290] Murillo, Julieth, 2020-01-07 [InstanceEdit:9673783] Murillo, Julieth, Jassal, Bijay, 2020-01-09
eventOf	[Pathway:R-HSA-9673324] WNT5:FZD7-mediated leishmania damping - Homo sapiens
followingEvent	[Reaction:R-HSA-9673296] WNT5:FZD7 binds p-DVL - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-517394] FZD7 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-3247777] N4GlycoAsn-PalmS WNT5A(36-380) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9673339] Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization [LiteratureReference:9673330] WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	WNT5 binds FZD7
output	[Complex:R-HSA-9673287] WNT5:FZD7 [plasma membrane]
precedingEvent	[Reaction:R-HSA-3247843] secretion of WNT ligands - Homo sapiens
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9675734] Gregory, David J, 2020-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9673349
summation	[Summation:9673294] Non-canonical WNT5A pathways (the ones that do not induce th...

Referrals

(hasEvent)	[Pathway:R-HSA-9673324] WNT5:FZD7-mediated leishmania damping
(precedingEvent)	[Reaction:R-HSA-9673296] WNT5:FZD7 binds p-DVL

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