Reactome | F9(227-461) G409V [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9671008] Shamovsky, Veronica, 2019-12-18
crossReference	[DatabaseIdentifier:12020816] Mondo:0010604
dbId	9671020
disease	[Disease:9670882] hemophilia B
displayName	F9(227-461) G409V [plasma membrane]
endCoordinate	461
hasModifiedResidue	[ReplacedResidue:9671022] glycine 409 replaced with L-valine
inDisease	true
literatureReference	[LiteratureReference:9671011] Experimental and theoretical evidence supporting the role of Gly363 in blood coagulation factor IXa (Gly193 in chymotrypsin) for proper activation of the proenzyme
maxDepth	1
memberOf	[CandidateSet:R-HSA-9670837] F9(227-461) variant [plasma membrane] - Homo sapiens
name	F9(227-461) G409V factor IXa heavy chain G409V factor IX Eagle Rock
referenceEntity	[ReferenceGeneProduct:uniprot:P00740] UniProt:P00740 F9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9671020
startCoordinate	227

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