Reactome | F9(29-461) Y450C [endoplasmic reticulum lumen]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9670828] Shamovsky, Veronica, 2019-12-17
dbId	9670822
displayName	F9(29-461) Y450C [endoplasmic reticulum lumen]
endCoordinate	461
hasModifiedResidue	[ReplacedResidue:9670917] L-tyrosine 450 replaced with L-cysteine
inDisease	false
literatureReference	[LiteratureReference:9670906] Replacement of the Y450 (c234) phenyl ring in the carboxyl-terminal region of coagulation factor IX causes pleiotropic effects on secretion and enzyme activity
memberOf	[CandidateSet:R-HSA-9670852] Non-secretable F9 variant [endoplasmic reticulum lumen] - Homo sapiens
name	F9(29-461) Y450C factor IX propeptide Y450C
referenceEntity	[ReferenceGeneProduct:54610] UniProt:P00740 F9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9670822
startCoordinate	29

(hasMember)

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