Reactome | p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9670417] Dimerization of STATs downstream of KIT mutants - Homo sapiens
created	[InstanceEdit:9670367] Rothfels, Karen, 2019-12-09
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9670369
disease	[Disease:1500689] cancer
displayName	p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane]
hasComponent	[Complex:R-HSA-9670368] KIT mutant dimers:SFKs [plasma membrane] 2 × [DefinedSet:R-HSA-1433413] p-STATs [cytosol] 2 × [EntityWithAccessionedSequence:R-HSA-873799] p-Y1007-JAK2 [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	6
name	p-JAK2:SFKs:p-KIT mutants:p-STATs
producedByEvent	[BlackBoxEvent:R-HSA-9670412] Phosphorylation of STATs downstream of KIT mutants - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9670369

(output)	[BlackBoxEvent:R-HSA-9670412] Phosphorylation of STATs downstream of KIT mutants
(input)	[Reaction:R-HSA-9670417] Dimerization of STATs downstream of KIT mutants
(diseaseEntity)	[EntityFunctionalStatus:9670398] gain_of_function of p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane]

Cite Us!