Reactome | p7Y-KIT D816A [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9669820] p7Y-kinase domain KIT mutants [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9669599] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12021297] Mondo:0005040 [DatabaseIdentifier:9669299] COSMIC:COSV55388612
dbId	9669629
disease	[Disease:1500689] cancer [Disease:9659308] germ cell cancer [Disease:9630839] acute myeloid leukemia
displayName	p7Y-KIT D816A [plasma membrane]
endCoordinate	976
hasModifiedResidue	[ReplacedResidue:9669430] L-aspartic acid 816 replaced with L-alanine [ModifiedResidue:205176] O4'-phospho-L-tyrosine at 568 [ModifiedResidue:205169] O4'-phospho-L-tyrosine at 570 [ModifiedResidue:205278] O4'-phospho-L-tyrosine at 703 [ModifiedResidue:205171] O4'-phospho-L-tyrosine at 721 [ModifiedResidue:205288] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:205235] O4'-phospho-L-tyrosine at 823 [ModifiedResidue:205246] O4'-phospho-L-tyrosine at 936
inDisease	true
maxDepth	1
modified	[InstanceEdit:9671517] Rothfels, Karen, 2019-12-19
name	p7Y-KIT D816A Mast/stem cell growth factor receptor precursor KIT_HUMAN c-KIT
referenceEntity	[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9669629
startCoordinate	26

(hasCandidate)

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