Reactome | p7Y-KIT D816N [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9669820] p7Y-kinase domain KIT mutants [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9669599] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12020751] Mondo:0005105 [DatabaseIdentifier:9669319] COSMIC:COSM133786
dbId	9669611
disease	[Disease:1500689] cancer [Disease:1614289] melanoma
displayName	p7Y-KIT D816N [plasma membrane]
endCoordinate	976
hasModifiedResidue	[ReplacedResidue:9669493] L-aspartic acid 816 replaced with L-asparagine [ModifiedResidue:205176] O4'-phospho-L-tyrosine at 568 [ModifiedResidue:205169] O4'-phospho-L-tyrosine at 570 [ModifiedResidue:205278] O4'-phospho-L-tyrosine at 703 [ModifiedResidue:205171] O4'-phospho-L-tyrosine at 721 [ModifiedResidue:205288] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:205235] O4'-phospho-L-tyrosine at 823 [ModifiedResidue:205246] O4'-phospho-L-tyrosine at 936
inDisease	true
maxDepth	1
modified	[InstanceEdit:9766312] D'Eustachio, Peter, 2022-02-18
name	p7Y-KIT D816N Mast/stem cell growth factor receptor precursor KIT_HUMAN c-KIT
referenceEntity	[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9669611
startCoordinate	26
updateTrackers	[UpdateTracker:9903174] Update Tracker - [EntityWithAccessionedSequence:9669611] p7Y-KIT D816N [plasma membrane] - v80:[add_removeHasModifiedResidue]

(updatedInstance)	[UpdateTracker:9903174] Update Tracker - [EntityWithAccessionedSequence:9669611] p7Y-KIT D816N [plasma membrane] - v80:[add_removeHasModifiedResidue]
(hasCandidate)	[CandidateSet:R-HSA-9669820] p7Y-kinase domain KIT mutants [plasma membrane]

Cite Us!