Reactome | p7Y-KIT V560G [plasma membrane]

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p7Y-KIT V560G [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9669808] p7Y-KIT V560G dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9669808] p7Y-KIT V560G dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9669599] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12020834] Mondo:0011719 [DatabaseIdentifier:9669345] COSMIC:COSM24838 [DatabaseIdentifier:9669326] COSMIC:COSV55393278
dbId	9669610
disease	[Disease:9661830] gastrointestinal stromal tumor [Disease:1500689] cancer [Disease:6802336] hematologic cancer
displayName	p7Y-KIT V560G [plasma membrane]
endCoordinate	976
hasModifiedResidue	[ReplacedResidue:9669533] L-valine 560 replaced with glycine [ModifiedResidue:205176] O4'-phospho-L-tyrosine at 568 [ModifiedResidue:205169] O4'-phospho-L-tyrosine at 570 [ModifiedResidue:205278] O4'-phospho-L-tyrosine at 703 [ModifiedResidue:205171] O4'-phospho-L-tyrosine at 721 [ModifiedResidue:205288] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:205235] O4'-phospho-L-tyrosine at 823 [ModifiedResidue:205246] O4'-phospho-L-tyrosine at 936
inDisease	true
literatureReference	[LiteratureReference:9669122] Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
maxDepth	1
name	p7Y-KIT V560G Mast/stem cell growth factor receptor precursor KIT_HUMAN c-KIT
referenceEntity	[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9669610
startCoordinate	26

Referrals

(hasComponent)

[Complex:R-HSA-9669808] p7Y-KIT V560G dimer [plasma membrane]

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