Reactome | p-Y-ERBB2 Y772_A775dup [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9665641] Orlic-Milacic, Marija, 2019-10-31
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9667193] COSMIC:COSM6024548
dbId	9665652
deleted	[Deleted:9831510] Deletion of instance: 9665656
disease	[Disease:1500689] cancer
displayName	p-Y-ERBB2 Y772_A775dup [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[FragmentInsertionModification:9665624] Insertion of residues 772 to 775 at 776 from UniProt:P04626 ERBB2 [ModifiedResidue:1678588] O4'-phospho-L-tyrosine at unknown position
inDisease	true
literatureReference	[LiteratureReference:9831359] Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site: New Routes to Targeted Therapies
maxDepth	1
memberOf	[CandidateSet:R-HSA-9664656] p-Y-ERBB2 KD mutants (ERBB3,PI3K) [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9831494] Orlic-Milacic, Marija, 2023-03-21
name	p-Y-ERBB2 Y772_A775dup p-Y-ERBB2 Tyr772_Ala775dup
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9665652
startCoordinate	23
updateTrackers	[UpdateTracker:9905309] Update Tracker - [EntityWithAccessionedSequence:9665652] p-Y-ERBB2 Y772_A775dup [plasma membrane] - v85:[addLiteratureReference, modifyName]

(updatedInstance)	[UpdateTracker:9905309] Update Tracker - [EntityWithAccessionedSequence:9665652] p-Y-ERBB2 Y772_A775dup [plasma membrane] - v85:[addLiteratureReference, modifyName]
(replacementInstances)	[Deleted:9831510] Deletion of instance: 9665656
(hasMember)	[CandidateSet:R-HSA-9664656] p-Y-ERBB2 KD mutants (ERBB3,PI3K) [plasma membrane]

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