Reactome | p-6Y-ERBB2 G309A [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9665383] Orlic-Milacic, Marija, 2019-10-30
crossReference	[DatabaseIdentifier:12020748] Mondo:0007254 [DatabaseIdentifier:9665351] COSMIC:COSV54066376
dbId	9665381
disease	[Disease:1500576] breast cancer [Disease:1500689] cancer
displayName	p-6Y-ERBB2 G309A [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9665341] glycine 309 replaced with L-alanine [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease	true
literatureReference	[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
maxDepth	1
memberOf	[CandidateSet:R-HSA-9665392] p-6Y-ERBB2 ECD mutants [plasma membrane] - Homo sapiens
name	p-6Y-ERBB2 G309A p-6Y-ERBB2 Gly309Ala
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9665381
startCoordinate	23

(hasMember)

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