Reactome | Transcription of PPP1R15A

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Transcription of PPP1R15A Show undefined attributes

authored	[InstanceEdit:9654242] May, Bruce, 2019-07-18
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9654769] May, Bruce, 2019-07-19
dbId	9654774
displayName	Transcription of PPP1R15A
edited	[InstanceEdit:9654242] May, Bruce, 2019-07-18
eventOf	[Pathway:R-HSA-9648895] Response of EIF2AK1 (HRI) to heme deficiency - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9654771] Transcription of Ppp1r15a - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9654776] PPP1R15A gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9655108] Mammalian GADD34, an apoptosis- and DNA damage-inducible gene [LiteratureReference:9655102] Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors [LiteratureReference:9655106] Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transcription of PPP1R15A
output	[EntityWithAccessionedSequence:R-HSA-9650727] PPP1R15A mRNA [cytosol]
precedingEvent	[Reaction:R-HSA-9654752] ATF4 binds the PPP1R15A (GADD34) promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9654777] Positive gene expression regulation by 'ATF4:PPP1R15A gene [nucleoplasm]'
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9664254] Chen, Jane-Jane, 2019-10-22
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9654774
summation	[Summation:9655062] The PPP1R15A (GADD34) gene is transcribed to yield mRNA (Hol...

Referrals

(hasEvent)	[Pathway:R-HSA-9648895] Response of EIF2AK1 (HRI) to heme deficiency
(inferredTo)	[BlackBoxEvent:R-MMU-9654771] Transcription of Ppp1r15a

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