Reactome | Translation of ATF5

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Translation of ATF5 Show undefined attributes

authored	[InstanceEdit:9653732] May, Bruce, 2019-07-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9653734] May, Bruce, 2019-07-15
dbId	9653745
displayName	Translation of ATF5
edited	[InstanceEdit:9653732] May, Bruce, 2019-07-14
eventOf	[Pathway:R-HSA-9648895] Response of EIF2AK1 (HRI) to heme deficiency - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9653710] Translation of Atf5 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9653717] ATF5-201 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9653730] Stress-induced translation of ATF5 mRNA is regulated by the 5'-untranslated region [LiteratureReference:9655797] The 5'-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translation of ATF5
output	[EntityWithAccessionedSequence:R-HSA-9653719] ATF5 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9648888] p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) - Homo sapiens [BlackBoxEvent:R-HSA-9653724] Transcription of ATF5 - Homo sapiens
regulatedBy	[PositiveRegulation:R-HSA-420845] Positive regulation by 'p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol]'
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9664254] Chen, Jane-Jane, 2019-10-22
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9653745
summation	[Summation:9653799] The ATF5 mRNA is translated to yield ATF5 protein (Watatani ...

Referrals

(hasEvent)	[Pathway:R-HSA-9648895] Response of EIF2AK1 (HRI) to heme deficiency
(inferredTo)	[BlackBoxEvent:R-MMU-9653710] Translation of Atf5

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