Reactome | KRAS L19F [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9653098] Rothfels, Karen, 2019-07-09
crossReference	[DatabaseIdentifier:12021095] Mondo:0002334 [DatabaseIdentifier:9653048] COSMIC:COSV55521217 [DatabaseIdentifier:9653059] COSMIC:COSV55502103
dbId	9653097
disease	[Disease:6802336] hematologic cancer [Disease:4791250] colorectal cancer [Disease:9646847] urinary system cancer
displayName	KRAS L19F [plasma membrane]
endCoordinate	186
hasModifiedResidue	[ReplacedResidue:9653028] L-leucine 19 replaced with L-phenylalanine
inDisease	true
literatureReference	[LiteratureReference:9652998] Characterization of a novel oncogenic K-ras mutation in colon cancer [LiteratureReference:9653003] Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine
maxDepth	1
memberOf	[CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane] - Homo sapiens
name	KRAS L19F
referenceEntity	[ReferenceGeneProduct:uniprot:P01116] UniProt:P01116 KRAS
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9653097
startCoordinate	1

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