Reactome | MAP2K1 G128D [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9652122] MAP2K1 G128D dimer [cytosol] - Homo sapiens [Complex:R-HSA-9652122] MAP2K1 G128D dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9652044] Rothfels, Karen, 2019-06-27
crossReference	[DatabaseIdentifier:12020752] Mondo:0005575 [DatabaseIdentifier:9651788] COSMIC:COSV61068347
dbId	9652043
disease	[Disease:4791250] colorectal cancer [Disease:1614289] melanoma
displayName	MAP2K1 G128D [cytosol]
endCoordinate	393
hasModifiedResidue	[ReplacedResidue:9651902] glycine 128 replaced with L-aspartic acid
inDisease	true
maxDepth	1
name	MAP2K1 G128D MEK1 Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Dual specificity mitogen-activated protein kinase kinase 1 MAP kinase kinase 1 MAPKK 1 ERK activator kinase 1 MAPK/ERK kinase 1
referenceEntity	[ReferenceGeneProduct:uniprot:Q02750] UniProt:Q02750 MAP2K1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9652043
startCoordinate	2

(hasComponent)

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