Reactome | ASIC trimers bind H+

Schema > Reaction > Entries

ASIC trimers bind H+ Show undefined attributes

authored	[InstanceEdit:2671892] Jassal, Bijay, 2012-11-26
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9650166] Jassal, Bijay, 2019-06-20
dbId	9650165
displayName	ASIC trimers bind H+
edited	[InstanceEdit:2671892] Jassal, Bijay, 2012-11-26
eventOf	[Pathway:R-HSA-2672351] Stimuli-sensing channels - Homo sapiens
followingEvent	[Reaction:R-HSA-2671885] ASIC trimers:H+ transport extracellular Na+ to cytosol - Homo sapiens
input	[DefinedSet:R-HSA-9650164] ASIC trimers [plasma membrane] [SimpleEntity:R-ALL-351626] H+ [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2671944] BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels [LiteratureReference:2671964] Cloning and expression of a novel human brain Na+ channel [LiteratureReference:2671955] Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis [LiteratureReference:2671968] Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel [LiteratureReference:2671974] Molecular cloning, functional expression and chromosomal localization of an amiloride-sensitive Na(+) channel from human small intestine [LiteratureReference:2672332] Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors [LiteratureReference:2672345] Regulation of ASIC activity by ASIC4--new insights into ASIC channel function revealed by a yeast two-hybrid assay
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ASIC trimers bind H+
orthologousEvent	[Reaction:R-CEL-9650165] ASIC trimers bind H+ - Caenorhabditis elegans [Reaction:R-GGA-9650165] ASIC trimers bind H+ - Gallus gallus [Reaction:R-XTR-9650165] ASIC trimers bind H+ - Xenopus tropicalis [Reaction:R-DRE-9650165] ASIC trimers bind H+ - Danio rerio [Reaction:R-SSC-9650165] ASIC trimers bind H+ - Sus scrofa [Reaction:R-BTA-9650165] ASIC trimers bind H+ - Bos taurus [Reaction:R-CFA-9650165] ASIC trimers bind H+ - Canis familiaris [Reaction:R-RNO-9650165] ASIC trimers bind H+ - Rattus norvegicus [Reaction:R-MMU-9650165] ASIC trimers bind H+ - Mus musculus
output	[DefinedSet:R-HSA-2671886] ASIC trimers:H+ [plasma membrane]
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3002750] He, Lei, 2013-01-28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9650165
summation	[Summation:9650163] Acid-sensing ion channels 1, 2, 3 and 5 (ASIC1, 2, 3 and 5, ...

Referrals

(hasEvent)	[Pathway:R-HSA-2672351] Stimuli-sensing channels
(precedingEvent)	[Reaction:R-HSA-2671885] ASIC trimers:H+ transport extracellular Na+ to cytosol

Cite Us!