Reactome | Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2

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Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
created	[InstanceEdit:964826] Jassal, B, 2010-09-17
dbId	964827
displayName	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
edited	[InstanceEdit:964826] Jassal, B, 2010-09-17
eventOf	[Pathway:R-HSA-964739] N-glycan trimming and elongation in the cis-Golgi - Homo sapiens
figure	[Figure:964833] /figures/man1a1_a2_c1.png
goBiologicalProcess	[GO_BiologicalProcess:6792152] Golgi apparatus N-glycan mannose trimming
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-964737] Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 - Homo sapiens [Reaction:R-HSA-964825] Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 - Homo sapiens [Reaction:R-HSA-964830] Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:964748] Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis
maxDepth	2
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
orthologousEvent	[Pathway:R-BTA-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Bos taurus [Pathway:R-DDI-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Dictyostelium discoideum [Pathway:R-CEL-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Caenorhabditis elegans [Pathway:R-DME-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Drosophila melanogaster [Pathway:R-GGA-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Gallus gallus [Pathway:R-XTR-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Xenopus tropicalis [Pathway:R-DRE-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Danio rerio [Pathway:R-SSC-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Sus scrofa [Pathway:R-CFA-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Canis familiaris [Pathway:R-RNO-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Rattus norvegicus [Pathway:R-MMU-964827] Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 - Mus musculus
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-964827
summation	[Summation:964733] In the cis-Golgi, Man7, Man8 or Man9 N-glycans are progressi...

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[Pathway:R-HSA-964739] N-glycan trimming and elongation in the cis-Golgi