Reactome | p-6Y-ERBB2 R896C [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

p-6Y-ERBB2 R896C [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019-05-30
crossReference	[DatabaseIdentifier:12021303] Mondo:0005580 [DatabaseIdentifier:9646724] COSMIC:COSV54075846
dbId	9647208
disease	[Disease:1500689] cancer [Disease:1500576] breast cancer [Disease:1996318] astrocytoma [Disease:9630862] esophagus squamous cell carcinoma
displayName	p-6Y-ERBB2 R896C [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9646716] L-arginine 896 replaced with L-cysteine [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease	true
literatureReference	[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
maxDepth	1
memberOf	[CandidateSet:R-HSA-9664612] p-6Y-ERBB2 KD mutants (EGFR) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9664999] p-6Y-ERBB2 KD mutants (EGFR,RAS) [plasma membrane] - Homo sapiens
name	p-6Y-ERBB2 R896C p-6Y-HER2 R896C p-6Y-ERBB2 Arg896Cys p-6Y-HER2 Arg896Cys
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9647208
startCoordinate	23

Referrals

(hasMember)

© 2026 Reactome

Cite Us!