Reactome | p-6Y-ERBB2 L755M [plasma membrane]

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p-6Y-ERBB2 L755M [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019-05-30
crossReference	[DatabaseIdentifier:12020752] Mondo:0005575 [DatabaseIdentifier:9646520] COSMIC:COSV54062219
dbId	9647204
disease	[Disease:1500689] cancer [Disease:1500576] breast cancer [Disease:6802273] skin melanoma [Disease:1248674] large intestine cancer
displayName	p-6Y-ERBB2 L755M [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9646535] L-leucine 755 replaced with L-methionine [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease	true
literatureReference	[LiteratureReference:9646515] Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma
maxDepth	1
name	p-6Y-ERBB2 L755M p-6Y-HER2 L755M p-6Y-ERBB2 Leu755Met p-6Y-HER2 Leu755Met
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9647204
startCoordinate	23

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