Reactome | p-6Y-ERBB2 H878R [plasma membrane]

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p-6Y-ERBB2 H878R [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019-05-30
crossReference	[DatabaseIdentifier:12020752] Mondo:0005575 [DatabaseIdentifier:9646856] COSMIC:COSV54070099
dbId	9647203
disease	[Disease:1500689] cancer [Disease:1248674] large intestine cancer
displayName	p-6Y-ERBB2 H878R [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9646821] L-histidine 878 replaced with L-arginine [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease	true
literatureReference	[LiteratureReference:9646931] Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
maxDepth	1
name	p-6Y-ERBB2 H878R p-6Y-HER2 H878R p-6Y-ERBB2 His878Arg p-6Y-HER2 His878Arg
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9647203
startCoordinate	23

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