Reactome | ERBB2 G778_P780dup [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

ERBB2 G778_P780dup [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9649456] ERBB2 KD mutants (osimertinib) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9665282] ERBB2 KD mutants (lapatinib resistant) [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9646669] Orlic-Milacic, Marija, 2019-05-27
crossReference	[DatabaseIdentifier:12020755] Mondo:0008903 [DatabaseIdentifier:9646666] COSMIC:COSV54065275 [DatabaseIdentifier:9646673] COSMIC:COSM21607 [DatabaseIdentifier:9646671] COSMIC:COSV54064411
dbId	9646667
deleted	[Deleted:9831561] Deletion of instance: 9665625
disease	[Disease:1500689] cancer [Disease:1500576] breast cancer [Disease:1500699] lung cancer
displayName	ERBB2 G778_P780dup [plasma membrane]
endCoordinate	1255
hasModifiedResidue	[FragmentInsertionModification:9646668] Insertion of residues 778 to 780 at 781 from UniProt:P04626 ERBB2
inDisease	true
literatureReference	[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
maxDepth	1
memberOf	[CandidateSet:R-HSA-9664580] ERBB2 KD mutants (EGFR) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9649470] ERBB2 KD mutants (sapitinib) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9665226] ERBB2 KD mutants (trastuzumab resistant) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9649436] ERBB2 KD mutants (neratinib) [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9646481] ERBB2 KD mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9831084] Orlic-Milacic, Marija, 2023-03-18
name	ERBB2 G778_P780dup HER2 G778_P780dup ERBB2 P780_Y781insGSP HER2 P780_Y781insGSP
referenceEntity	[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9646667
startCoordinate	23
updateTrackers	[UpdateTracker:9905320] Update Tracker - [EntityWithAccessionedSequence:9646667] ERBB2 G778_P780dup [plasma membrane] - v85:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905320] Update Tracker - [EntityWithAccessionedSequence:9646667] ERBB2 G778_P780dup [plasma membrane] - v85:[modifyName]
(replacementInstances)	[Deleted:9831561] Deletion of instance: 9665625
(hasMember)	[CandidateSet:R-HSA-9665226] ERBB2 KD mutants (trastuzumab resistant) [plasma membrane] [CandidateSet:R-HSA-9646481] ERBB2 KD mutants [plasma membrane] [CandidateSet:R-HSA-9649436] ERBB2 KD mutants (neratinib) [plasma membrane] [CandidateSet:R-HSA-9649470] ERBB2 KD mutants (sapitinib) [plasma membrane] [CandidateSet:R-HSA-9649458] ERBB2 KD mutants (afatinib) [plasma membrane] [CandidateSet:R-HSA-9664580] ERBB2 KD mutants (EGFR) [plasma membrane]
(hasCandidate)	[CandidateSet:R-HSA-9665282] ERBB2 KD mutants (lapatinib resistant) [plasma membrane] [CandidateSet:R-HSA-9649456] ERBB2 KD mutants (osimertinib) [plasma membrane]